| The Road Is Rough and Rocky | Archie Edwards | 3:27 | |
| Things Have Changed | Big Maceo | 3:00 | |
| I Feel So Good | J.B. Lenoir | 1:54 | |
| Black Snake Moan | Blind Lemon Jefferson | 2:50 | |
| Aberdeen Mississippi Blues | Bukka White | 2:35 | |
| Step It up and Go | Blind Boy Fuller | 2:59 | |
| Travelin' Higway Man | Tommy McClennan | 2:59 | |
| Levee Camp Blues | Son House | 3:45 | |
| Downtown Blues | Frank Stokes | 3:17 | |
| That's All Right | Arthur "Big Boy" Crudup | 2:24 | |
| Cornbread, Peas and Black Molasses | Sonny Terry and Brownie McGhee | 2:31 | |
| T.B. Blues | Champion Jack Dupree | 3:42 | |
| Jesus Make Up My Dying Bed | Blind Willie Johnson | 3:10 | |
| Shake 'Em On Down | Bukka White | 3:37 | |
| Cocaine Done Kill My Baby | Mance Lipscomb | 2:33 | |
| When You Always By Yourself | Lonnie Johnson | 2:58 | |
| He's In The Jail House Now | Memphis Jug Band | 3:12 | |
| Charmin' Betsy | Henry Thomas | 3:01 | |
| Let Me Roll Your Lemon | Bo Carter | 2:56 | |
| Guitar Rag | Sylvester Weaver | 3:06 | |
| T.B. Blues | Leon Redbone | 4:51 | |
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| On The Road Again | Memphis Jug Band | 2:48 | |
| You Got to Die | Blind Willie McTell | 3:12 | |
| The Entire Family Was Musicians | Lonnie Johnson | 4:38 | |
| Nobody Knows When You're Down | Big Joe Williams | 3:26 | |
| Trouble Mind | Sonny Terry and Brownie McGhee | 3:26 | |
| Things 'Bout Comin' My Way | Tampa Red | 3:13 | |
| Sagefield Woman Blues | Kokomo Arnold | 3:04 | |
| Screamin' and Hollerin' the Blues | Charley Patton | 3:05 | |
| Worried About My Baby | Sunnyland Slim | 2:41 | |
| Statesboro Blues | Blind Willie McTell | 2:32 | |
| Feelin' Good | J.B. Lenoir | 3:01 | |
| See That My Grave's Kept Clean | Blind Lemon Jefferson | 2:53 | |
| Rollin' Stone, Pt. 1 | Robert Wilkins | 2:53 | |
| Minglewood Blues | Cannon's Jug Stompers | 3:40 | |
| Long Road to Travel | Lonnie Johnson | 2:22 | |
| I'm the Midnight Creeper (feat.Shuggie Otis) | Eddie "Cleanhead" Vinson, Johnny Otis, Shuggie Otis | 3:29 | |
| Dark Road Blues | Willie Lofton | 3:03 | |
| Ain't Seen My Baby | Cephas & Wiggins | 3:22 | |
| Alabama Blues | J.B. Lenoir | 3:14 | |
| Pearline | Son House | 4:31 | |
| Sloppy Drunk - Single Version | Jimmy Rogers | 3:02 | |
| Blues All Day Long (Blues Leave Me Alone) - Single Version | Jimmy Rogers | 3:05 | |
| Pure Religion | Rev. Gary Davis | 2:57 | |
| Blue Guitar | Earl Hooker | 2:46 | |
| Little Boy Blue | Scrapper Blackwell | 3:07 | |
| Weak Brain, Narrow Mind | Willie Dixon | 4:25 | |
| Blues Hangover | Slim Harpo | 3:06 | |
| Lockwood's Boogie | Robert Lockwood, Jr. | 2:26 | |