| Big Six | Matt "Guitar" Murphy | 4:52 | |
| That's All Right | Arthur "Big Boy" Crudup | 2:24 | |
| I Ain't Never | Jimmie Vaughan | 3:04 | |
| Too Far Gone (feat. Jimmie Vaughan) | The Texas Horns, Jimmie Vaughan | 4:24 | |
| Satisfy Suzie | Lonnie Mack | 4:57 | |
| Drinking Straight Tequila | Chris Cain | 2:52 | |
| Hello Mary Lee | Omar Kent Dykes, Jimmie Vaughan, Lazy Lester | 2:28 | |
| Be My Lovey Dovey | Jimmie Vaughan | 3:14 | |
| Love Gone to Waste | The Robert Cray Band | 4:13 | |
| Crazy Love | Long John Hunter | 5:41 | |
| These Blues Is Killing Me | A.C. Reed | 3:07 | |
| Too Drunk To Drive Drunk | Joe Louis Walker | 3:56 | |
| Riding The Blinds | Lonnie Mack | 4:22 | |
| Lucky Guy | Nick Moss Band, Dennis Gruenling | 4:32 | |
| If You Were Mine | Lil Ed & The Blues Imperials | 2:44 | |
| Crazy 'Bout My Baby | Snooky Pryor | 3:34 | |
| Mr. Smith | Delbert McClinton, Self-Made-Men | 4:02 | |
| Broke and Hungry | Hubert Sumlin | 5:51 | |
| Gotta Move On | Eddy Clearwater | 4:40 | |
| Pawnshop Bound | William Clarke | 4:23 | |
| Bluz Crazy | Tom Hambridge | 3:59 | |
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| Think | Omar Kent Dykes, Jimmie Vaughan, Lou Ann Barton | 3:49 | |
| Bluesman for Life - Remastered | Roy Gaines | 5:10 | |
| Six Strings Down | Jimmie Vaughan | 3:28 | |
| Change It | Doyle Bramhall | 3:02 | |
| Sweet Home Chicago | Lonnie Brooks | 4:55 | |
| So Long (for Jay P.) | Rick Estrin & The Nightcats | 3:23 | |
| Strike Like Lightning | Lonnie Mack | 3:43 | |
| Greasy Gravy | William Clarke | 3:34 | |
| Bad Axe | Son Seals | 3:13 | |
| Two Bugs and a Roach | Earl Hooker | 4:19 | |
| It Came out of Nowhere | Damon Fowler | 2:55 | |
| I'm A Blues Man | Kenny Neal | 4:11 | |
| I Smell Smoke | Michael Burks | 3:50 | |
| I Can't Hear Nothing But The Blues | Son Seals | 6:35 | |
| I Ain't Got You | Jimmy Reed | 2:15 | |
| Bury You in a Paper Sack | Snooky Pryor | 4:35 | |
| My Texas Home | W.C. Clark | 4:53 | |
| Brothers | The Vaughan Brothers | 5:05 | |
| One of These Days | Slim Harpo | 2:49 | |
| Gotta Get It Worked On | Delbert McClinton | 4:01 | |
| Hoodoo on Me | Albert Castiglia | 3:34 | |
| Giving Up On Your Love | Lil Ed & The Blues Imperials | 3:39 | |
| Have A Good Time | Big Walter Horton | 3:48 | |
| Get Busy | Guitar Shorty | 3:41 | |
| Talk to Me Baby - Remastered | The Blues Band | 3:54 | |
| Blues For The Hook (Dedicated To John Lee Hooker) | The James Cotton Blues Band, Jimmie Vaughan | 6:09 | |
| Friar's Point | Susan Tedeschi | 4:23 | |
| One Scotch, One Bourbon, One Beer - Bonus Track | Champion Jack Dupree | 4:14 | |
