| If It Had Not Been For Jesus | Blind Willie Johnson | 3:23 | |
| Sugar Baby | Dock Boggs | 2:57 | |
| The Road Is Rough and Rocky | Archie Edwards | 3:27 | |
| You Got to Die | Blind Willie McTell | 3:12 | |
| Cool Drink Of Water | Houston Stackhouse | 3:16 | |
| Nobody Knows You When You're Down and Out - 78rpm Version | Bessie Smith | 2:56 | |
| Pin in Your Cushion | Bo Carter | 3:06 | |
| Mississippi Heavy Water Blues | Barbecue Bob | 3:09 | |
| Let's Disagree | Leroy Carr | 2:56 | |
| Go Ahead, Buddy | Casey Bill Weldon, Kokomo Arnold | 2:44 | |
| Down South Blues | Dock Boggs | 2:11 | |
| How Long | Frank Stokes | 3:18 | |
| Walk Right In | Cannon's Jug Stompers | 2:55 | |
| Midnight Special - Remastered 2002 | Lead Belly | 3:05 | |
| I'm A Bad Luck Woman | Memphis Minnie | 3:00 | |
| Trouble Soon Be Over | Blind Willie Johnson | 3:07 | |
| Charmin' Betsy | Henry Thomas | 3:01 | |
| Going to Germany | Cannon's Jug Stompers | 2:31 | |
| Old Dog Blue | Jim Jackson | 2:58 | |
| Charley Bostock's Blues | C.W. Stoneking | 3:34 | |
| Ain't You Sorry | Mance Lipscomb | 2:20 | |
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| You're Gonna Need Somebody When You Die | Charley Patton | 2:55 | |
| That's All Right, Pt. 1 | John Henry Barbee | 3:40 | |
| Diggin' My Potatoes | Washboard Sam | 2:58 | |
| Everybody Ought to Treat a Stranger Right | Blind Willie Johnson, Willie B. Richardson | 3:05 | |
| Revenue Man Blues | Charley Patton | 2:43 | |
| Mean Old Bedbug Blues | Furry Lewis | 2:45 | |
| The Half Ain't Never Been Told / Just Look / Come and See / God Moves on the Water / He Got Better Things for You / The Latter Rain Is Fall | Rev. F.W. McGee, Arizona Dranes, Rev. D.C. Rice, Blind Willie Johnson, Lonnie McIntorsh, Elder Edwards, The Memphis Sanctified Singers | 7:36 | |
| Rope Stretching Blues | Blind Blake | 3:02 | |
| Wade in the Water | Big Mama Thornton | 2:56 | |
| Blue Ghost Blues | Lonnie Johnson | 3:09 | |
| Graveyard Blues | Roscoe Holcomb | 3:01 | |
| Captain, Captain - Version; Take 2; Remastered | Mance Lipscomb | 2:34 | |
| Trouble Will Soon Be Over | Blind Willie Johnson | 3:09 | |
| Crazy Blues | Mamie Smith | 3:22 | |
| When The Levee Breaks | Memphis Minnie & Kansas Joe | 3:08 | |
| The Prodigal Son | Robert Wilkins | 10:00 | |
| Little Rain | Jimmy Reed | 3:09 | |
| Rock Me Mama | Arthur "Big Boy" Crudup | 2:29 | |
| Falling Down Blues | Furry Lewis | 2:48 | |
| Further Up on the Road | David "Honeyboy" Edwards | 4:20 | |
| Fallin' Down Blues | Robert Wilkins | 2:38 | |
| It Hurts Me Too | Elmore James | 3:12 | |
| Sitting On Top Of The World | Mississippi Sheiks | 3:12 | |
| She-Wolf | Jessie Mae Hemphill | 4:41 | |
| Pure Religion | Rev. Gary Davis | 2:57 | |
| Blue Guitar | Earl Hooker | 2:46 | |
| Haunted House | Lonnie Johnson, Elmer Snowden | 5:00 | |
| Mother Earth | Memphis Slim | 2:39 | |