| Key To The Highway | Carey Bell, Lurrie Bell | 3:28 | |
| Man Ain't Nothing But A Fool | Sonny Terry and Brownie McGhee | 3:08 | |
| It Hurts Me Too | Snooky Pryor | 3:22 | |
| Pig Meat Is What I Crave | Bo Carter | 2:51 | |
| Rooster Blues | Lightnin' Slim | 2:44 | |
| Evil Blues | Melvin "Lil' Son" Jackson | 2:50 | |
| Crossroads | David "Honeyboy" Edwards | 3:26 | |
| Back Door Blues | Kokomo Arnold | 3:25 | |
| What You Doing to Me (feat. Victor Wainwright) | Brandon Santini, Victor Wainwright | 5:18 | |
| Roll and Tumble Blues - 1929 Version | Hambone Willie Newbern | 3:04 | |
| Fixin' to Die Blues | Bukka White | 2:51 | |
| Dig Myself a Hole | Arthur "Big Boy" Crudup | 2:23 | |
| Mississippi Boweavil Blues | Charley Patton | 3:11 | |
| Bad Luck Blues (Alternative Take) | Lightnin' Slim | 2:35 | |
| Black Snake Moan | Blind Lemon Jefferson | 2:50 | |
| Nobody's Fault But Mine | Johnny Shines | 4:45 | |
| Aberdeen Mississippi Blues | Bukka White | 2:35 | |
| Coal Black Mare | Snooky Pryor | 3:27 | |
| Chicago Breakdown | Big Maceo | 2:55 | |
| Everytime I Get to Drinking | Sunnyland Slim | 4:15 | |
| Texas Hop | Pee Wee Crayton | 3:06 | |
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| County Farm Blues | Son House | 2:12 | |
| Statesboro Blues | Blind Willie McTell | 2:32 | |
| Kansas City | Hound Dog Taylor | 3:50 | |
| So Glad You're Mine | Arthur "Big Boy" Crudup | 2:48 | |
| Catfish Blues | David "Honeyboy" Edwards | 3:30 | |
| Cross And Evil Woman Blues | Rev. Gary Davis | 3:02 | |
| Church Bells Blues | Luke Jordan | 3:15 | |
| Big Road Blues | Tommy Johnson | 3:12 | |
| Saturday Night Women | Big Joe Williams | 3:42 | |
| Broke Down Engine Blues | Blind Willie McTell | 3:11 | |
| Long Road to Travel | Lonnie Johnson | 2:22 | |
| What A Beautiful City | Sonny Terry and Brownie McGhee | 2:23 | |
| Baby Please Don’t Go | Big Joe Williams | 1:48 | |
| Better Day | Brownie McGhee, Sonny Terry | 3:03 | |
| I Feel So Good | J.B. Lenoir | 1:54 | |
| Walk On | Sonny Terry and Brownie McGhee | 3:11 | |
| Vineyard Blues | Joe Louis Walker | 3:29 | |
| Come To Me | Juke Boy Bonner | 2:54 | |
| Ice Cream Man | John Brim | 2:44 | |
| Take A Little Walk With Me | Robert Lockwood, Jr. | 3:38 | |
| The River's Invitation | Percy Mayfield | 2:51 | |
| Blue Guitar | Earl Hooker | 2:46 | |
| Goodbye Blues | Blind Willie McTell | 1:39 | |
| Luedella | Jimmy Rogers | 2:54 | |
| Harmonica Hop | Sonny Terry and Brownie McGhee | 2:41 | |
| I Was Born With The Blues | Sonny Terry and Brownie McGhee | 3:31 | |
| Walk On | Sonny Terry and Brownie McGhee | 3:11 | |
| Mother Earth | Memphis Slim | 2:39 | |